Dr. Ruth Perets is Director of the Women’s Cancer Laboratory and an Attending Physician and oncologist in the Oncology Division at Rambam Health Care Campus. Dr. Perets focuses her clinical work on gynecological malignancies, and she is the principal investigator of all Phase 1 clinical trials in Rambam’s Oncology Division. Dr. Perets was visiting the Hudson institute at Monash health, as part of an ongoing collaboration.
Dr. Perets spoke about ovarian cancer, a disease with grim prognosis, mostly because it is diagnosed at late stages, when it is widespread in patients, and no longer curable. This late stage of diagnosis has hindered for many years the attempts to understand where ovarian cancer starts. Dr. Perets discussed the finding that ovarian cancer often does not start from the ovary, but rather from the fallopian tube. She described the current evidence that this is indeed true, and detailed the implications to ovarian cancer prevention, especially in women at high familial risk for ovarian cancer. Dr. Perets also described the work currently done in her lab, explaining how the fallopian tube origin effects ovarian cancer biology. She showed how the fallopian tube origin can lead to future novel therapies, and better tailoring of therapy to specific patients.
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